List of 12 Erectile Dysfunction Medications Compared (2024)

Table of Contents
Drugs used to treat Erectile Dysfunction Frequently asked questions Alternative treatments for Erectile Dysfunction Learn more about Erectile Dysfunction Browse treatment options Further information

Other names: ED; Erection Problems; Impotence; Sexual Dysfunction, Male

A consistent inability to sustain an erection sufficient for sexual intercourse. Also commonly known as impotence. Medically, the term erectile dysfunction is used to differentiate impotence from other problems that interfere with sexual intercourse

See Also
What Is the Most Effective Pill for Erectile Dysfunction (ED)?Which drug for erectile dysfunction? - Harvard HealthED Medications: Types, Cost, and MoreBest Erectile Dysfunction Treatments Of 2024

Drugs used to treat Erectile Dysfunction

The medications listed below are related to or used in the treatment of this condition.

Drug nameRatingReviewsActivity?Rx/OTCPregnancyCSAAlcohol
Cialis8.6455 reviews for Cialis to treat Erectile DysfunctionRxBNX
Generic name:
tadalafil systemic
Drug class:
impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
sildenafil8.3434 reviews for sildenafil to treat Erectile DysfunctionRxBNX
Generic name:
sildenafil systemic
Brand name:
Viagra
Drug class:
impotence agents, agents for pulmonary hypertension
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Viagra8.5227 reviews for Viagra to treat Erectile DysfunctionRxBNX
Generic name:
sildenafil systemic
Drug class:
impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tadalafil8.4629 reviews for tadalafil to treat Erectile DysfunctionRxBNX
Generic name:
tadalafil systemic
Brand name:
Cialis
Drug class:
impotence agents, agents for pulmonary hypertension
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Caverject Impulse9.610 reviews for Caverject Impulse to treat Erectile DysfunctionRxXN
Generic name:
alprostadil systemic
Drug class:
vasodilators, impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
vardenafil8.0168 reviews for vardenafil to treat Erectile DysfunctionRxBNX
Generic name:
vardenafil systemic
Drug class:
impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
alprostadil7.1181 reviews for alprostadil to treat Erectile DysfunctionRxXN
Generic name:
alprostadil systemic
Brand names:
Caverject Impulse, Edex, Caverject, Muse
Drug class:
vasodilators, impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Edex7.548 reviews for Edex to treat Erectile DysfunctionRxXN
Generic name:
alprostadil systemic
Drug class:
vasodilators, impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Caverject7.027 reviews for Caverject to treat Erectile DysfunctionRxXN
Generic name:
alprostadil systemic
Drug class:
vasodilators, impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Muse5.254 reviews for Muse to treat Erectile DysfunctionRxXN
Generic name:
alprostadil systemic
Drug class:
vasodilators, impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Stendra5.659 reviews for Stendra to treat Erectile DysfunctionRxCNX
Generic name:
avanafil systemic
Drug class:
impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
avanafil5.761 reviews for avanafil to treat Erectile DysfunctionRxCNX
Generic name:
avanafil systemic
Brand name:
Stendra
Drug class:
impotence agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
See Also
What Is the Safest Drug for Erectile Dysfunction?

Frequently asked questions

  • Cialis vs Viagra - What's the difference between them?
  • Can you take Viagra with high blood pressure?
  • What is Eroxon?
  • Why does Cialis take at least 12-14 hours to work?
  • Does Cialis lower blood pressure?
  • Can women take Viagra?
  • Do you know these 11 amazing facts about Viagra?
  • Cialis: 7 Important Things to Know
  • How long does Viagra last and how soon does it work?

View more FAQ

Alternative treatments for Erectile Dysfunction

The following products are considered to be alternative treatments or natural remedies for Erectile Dysfunction. Their efficacymay not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical,cultural or anecdotal evidence linking their use to the treatment of Erectile Dysfunction.

  • Damiana
  • Horny Goat Weed
  • Yohimbine

Learn more about Erectile Dysfunction

  • Erectile Dysfunction Medications and Alcohol Interactions
  • Viagra: How a Little Blue Pill Changed the World

Care guides

  • Erectile Dysfunction

Symptoms and treatments

  • Impotence (Erectile Dysfunction)

Medicine.com guides (external)

Legend

RatingFor ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
ActivityActivity is based on recent site visitor activity relative to other medications in the list.
RxPrescription only.
OTCOver-the-counter.
Rx/OTCPrescription or Over-the-counter.
Off-labelThis medication may not be approved by the FDA for the treatment of this condition.
EUAAn Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded AccessExpanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
AAdequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
BAnimal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
CAnimal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
DThere is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
XStudies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
NFDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
MThe drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
UCSA Schedule is unknown.
NIs not subject to the Controlled Substances Act.
1Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
XInteracts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circ*mstances.

Medical Disclaimer

List of 12 Erectile Dysfunction Medications Compared (2024)
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